Colon Cancer
Colon cancer affects average 6% of the population. In some cases, people with a strong history track of colorectal cancer in their family may have a high risk of genetic predisposition to colon cancer.
Lynch syndrome and familial adenomatous polyposis are the most common Colon cancer syndromes. The massive sequencing or Next-generation Sequencing offers the possibility of analyzing 15 genes associated with different syndromes of hereditary colon cancer simultaneously. Some of these genes increase also the risk of developing other cancers such as breast, ovarian or pancreatic cancer.
Lynch syndrome and familial adenomatous polyposis are the most common Colon cancer syndromes. The massive sequencing or Next-generation Sequencing offers the possibility of analyzing 15 genes associated with different syndromes of hereditary colon cancer simultaneously. Some of these genes increase also the risk of developing other cancers such as breast, ovarian or pancreatic cancer.
Discover our ColonSeq (NGS Genetic test for colorectal cancer)
We strongly recommend to perform this test to:
For more information check Amsterdam and Bethesda clinical criteria.
The knowledge linked to a patient's genetic susceptibility to colon cancer may guide clinical management through:
- Patients for whom there is no clear diagnosis in relation to their specific type of colorectal cancer, but there is evidence of a clear hereditary component.
- Patients with a strong family history of colon cancer.
- Patients diagnosed with colon cancer before age 50.
For more information check Amsterdam and Bethesda clinical criteria.
The knowledge linked to a patient's genetic susceptibility to colon cancer may guide clinical management through:
- Establish procedures for monitoring and prevention measures (e.g. periodic colonoscopies).
- Surgical measures may be recommended in specific high-risk cases.
- Identification of treatment options.
- Identification of additional family members at high risk.
